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Mechanism of inhibition of mouse Slo3 (K(Ca)5.1) potassium channels by quinine, quinidine and barium

BACKGROUND AND PURPOSE: The Slo3 (K(Ca)5.1) channel is a major component of mammalian KSper (sperm potassium conductance) channels and inhibition of these channels by quinine and barium alters sperm motility. The aim of this investigation was to determine the mechanism by which these drugs inhibit S...

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書目詳細資料
發表在:Br J Pharmacol
Main Authors: Wrighton, David C, Muench, Stephen P, Lippiat, Jonathan D
格式: Artigo
語言:Inglês
出版: John Wiley & Sons, Ltd 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556473/
https://ncbi.nlm.nih.gov/pubmed/26045093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13214
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