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Elevated Plasma C-Terminal Endothelin-1 Precursor Fragment Concentrations Are Associated with Less Anxiety in Patients with Cardiovascular Risk Factors. Results from the Observational DIAST-CHF Study

BACKGROUND: The role of endothelin-1 (ET-1) in the neurobiology of anxiety is unknown, therefore, we assessed in the observational multicenter DIAST-CHF study whether the C-terminal ET-1 precursor fragment (CT-proET-1) is linked to anxiety. METHODS: Plasma concentrations of CT-proET-1 were measured...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Meyer, Thomas, Chavanon, Mira-Lynn, Herrrmann-Lingen, Christoph, Roggenthien, Maren, Nolte, Kathleen, Pieske, Burkert, Wachter, Rolf, Edelmann, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556459/
https://ncbi.nlm.nih.gov/pubmed/26322793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136739
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