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Loss of Cell–Cell Contacts Induces NF-κB Via RhoA-Mediated Activation of Protein Kinase D1
Cell–cell contacts mediated by cadherins are known to inhibit the small Rho-GTPase RhoA. We here show that in epithelial cells the disruption of these cell–cell contacts as mediated by a calcium switch leads to actin re-organization and the activation of RhoA. We identified the serine/threonine kina...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | J Cell Biochem |
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| Κύριοι συγγραφείς: | , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2009
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4556359/ https://ncbi.nlm.nih.gov/pubmed/19173301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.22067 |
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