Targeting the Cyclophilin Domain of Ran-binding Protein 2 (Ranbp2) with Novel Small Molecules to Control the Proteostasis of STAT3, hnRNPA2B1 and M-Opsin

Cyclophilins are peptidyl cis-trans prolyl isomerases (PPIases), whose activity is typically inhibited by cyclosporine A (CsA), a potent immunosuppressor. Cyclophilins are also chaperones. Emerging evidence supports that cyclophilins present non-overlapping PPIase and chaperone activities. The prote...

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Detaylı Bibliyografya
Yayımlandı:ACS Chem Neurosci
Asıl Yazarlar: Cho, Kyoung-in, Orry, Andrew, Park, Se Eun, Ferreira, Paulo A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556350/
https://ncbi.nlm.nih.gov/pubmed/26030368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.5b00134
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