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Crystallography and chemistry should always go together: a cautionary tale of protein complexes with cisplatin and carboplatin
The anticancer activity of platinum-containing drugs such as cisplatin and carboplatin is considered to primarily arise from their interactions with nucleic acids; nevertheless, these drugs, or the products of their hydrolysis, also bind to proteins, potentially leading to the known side effects of...
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| Publicado no: | Acta Crystallogr D Biol Crystallogr |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
International Union of Crystallography
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4556316/ https://ncbi.nlm.nih.gov/pubmed/26327386 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S139900471500629X |
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