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Crystallography and chemistry should always go together: a cautionary tale of protein complexes with cisplatin and carboplatin

The anticancer activity of platinum-containing drugs such as cisplatin and carboplatin is considered to primarily arise from their interactions with nucleic acids; nevertheless, these drugs, or the products of their hydrolysis, also bind to proteins, potentially leading to the known side effects of...

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Detaylı Bibliyografya
Yayımlandı:Acta Crystallogr D Biol Crystallogr
Asıl Yazarlar: Shabalin, Ivan, Dauter, Zbigniew, Jaskolski, Mariusz, Minor, Wladek, Wlodawer, Alexander
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: International Union of Crystallography 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556316/
https://ncbi.nlm.nih.gov/pubmed/26327386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S139900471500629X
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