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Thermodynamic procedure to synthesize heteropolymers that can renature to recognize a given target molecule.

We suggest a procedure to synthesize polymers with characteristics similar to those observed in globular proteins: renaturability and the existence of an "active site" capable of specifically recognizing a given target molecule. This procedure is investigated by computer simulation, which finds a yi...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Pande, V S, Grosberg, A Y, Tanaka, T
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 1994
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45563/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7809158/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.26.12976
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