Paraquat Induces Apoptosis through a Mitochondria-Dependent Pathway in RAW264.7 Cells

Paraquat dichloride (N,N-dimethyl-4-4′-bipiridinium, PQ) is an extremely toxic chemical that is widely used in herbicides. PQ generates reactive oxygen species (ROS) and causes multiple organ failure. In particular, PQ has been reported to be an immunotoxic agrochemical compound. PQ was shown to dec...

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Detalhes bibliográficos
Publicado no:Biomol Ther (Seoul)
Main Authors: Jang, Yeo Jin, Won, Jong Hoon, Back, Moon Jung, Fu, Zhicheng, Jang, Ji Min, Ha, Hae Chan, Hong, SeungBeom, Chang, Minsun, Kim, Dae Kyong
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Society of Applied Pharmacology 2015
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556199/
https://ncbi.nlm.nih.gov/pubmed/26336579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2015.075
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