EGFR mutation L747P led to gefitinib resistance and accelerated liver metastases in a Chinese patient with lung adenocarcinoma

Background: Mutations in the epidermal growth factor receptor gene (EGFR) are found in around half of Asian patients with non-small cell lung cancer (NSCLC). For this reason, EGFR tyrosine kinase inhibitors (TKI) are often prescribed depending on the EGFR status. Two common EGFR mutations, a deletio...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Int J Clin Exp Pathol
Main Authors: Yu, Guohua, Xie, Xiaoxia, Sun, Dengjun, Geng, Junzu, Fu, Fenghua, Zhang, Liangming, Wang, Hongbo
Format: Artigo
Jezik:Inglês
Izdano: e-Century Publishing Corporation 2015
Teme:
Case Report
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4555769/
https://ncbi.nlm.nih.gov/pubmed/26339441
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