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Comparison between two widely used laboratory methods in BRAF V600 mutation detection in a large cohort of clinical samples of cutaneous melanoma metastases to the lymph nodes

Aims: The study compares detection rates of oncogenic BRAF mutations in a homogenous group of 236 FFPE cutaneous melanoma lymph node metastases, collected in one cancer center. BRAF mutational status was verified by two independent in-house PCR/Sanger sequencing tests, and the Cobas® 4800 BRAF V600...

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Detalhes bibliográficos
Publicado no:Int J Clin Exp Pathol
Main Authors: Jurkowska, Monika, Gos, Aleksandra, Ptaszyński, Konrad, Michej, Wanda, Tysarowski, Andrzej, Zub, Renata, Siedlecki, Janusz A, Rutkowski, Piotr
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4555750/
https://ncbi.nlm.nih.gov/pubmed/26339422
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