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Cross-resistance to clinically used tyrosine kinase inhibitors sunitinib, sorafenib and pazopanib
PURPOSE: When during cancer treatment resistance to a tyrosine kinase inhibitor (TKI) occurs, switching to another TKI is often considered as a reasonable option. Previously, we reported that resistance to sunitinib may be caused by increased lysosomal sequestration, leading to increased intracellul...
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Publicado en: | Cell Oncol (Dordr) |
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Main Authors: | , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado: |
Springer Netherlands
2015
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Assuntos: | |
Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4555235/ https://ncbi.nlm.nih.gov/pubmed/25665527 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13402-015-0218-8 |
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