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Rapid Identification of Chemoresistance Mechanisms Using Yeast DNA Mismatch Repair Mutants

Resistance to cancer therapy is a major obstacle in the long-term treatment of cancer. A greater understanding of drug resistance mechanisms will ultimately lead to the development of effective therapeutic strategies to prevent resistance from occurring. Here, we exploit the mutator phenotype of mis...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:G3 (Bethesda)
Hauptverfasser: Ojini, Irene, Gammie, Alison
Format: Artigo
Sprache:Inglês
Veröffentlicht: Genetics Society of America 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4555229/
https://ncbi.nlm.nih.gov/pubmed/26199284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.115.020560
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