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Targeted Modification of Gene Function Exploiting Homology-Directed Repair of TALEN-Mediated Double-Strand Breaks in Barley

Transcription activator-like effector nucleases open up new opportunities for targeted mutagenesis in eukaryotic genomes. Similar to zinc-finger nucleases, sequence-specific DNA-binding domains can be fused with effector domains like the nucleolytically active part of FokI to induce double-strand br...

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Detalhes bibliográficos
Publicado no:G3 (Bethesda)
Main Authors: Budhagatapalli, Nagaveni, Rutten, Twan, Gurushidze, Maia, Kumlehn, Jochen, Hensel, Goetz
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4555222/
https://ncbi.nlm.nih.gov/pubmed/26153077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.115.018762
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