PI4K-beta and MKNK1 are regulators of hepatitis C virus IRES-dependent translation

Cellular translation is down-regulated by host antiviral responses. Picornaviridae and Flaviviridae including hepatitis C virus (HCV) evade this process using internal ribosomal entry sequences (IRESs). Although HCV IRES translation is a prerequisite for HCV replication, only few host factors critic...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lupberger, Joachim, Casanova, Claudia, Fischer, Benoit, Weiss, Amelie, Fofana, Isabel, Fontaine, Nelly, Fujiwara, Toshinobu, Renaud, Mickael, Kopp, Arnaud, Schuster, Catherine, Brino, Laurent, Baumert, Thomas F., Thoma, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4555030/
https://ncbi.nlm.nih.gov/pubmed/26323588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13344
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