Antibody-free quantification of seven tau peptides in human CSF using targeted mass spectrometry

Tau protein concentration in cerebrospinal fluid (CSF) is currently used as a sensitive and specific biomarker for Alzheimer's disease. Its detection currently relies on ELISA but the perspective of using mass spectrometry (MS) to detect its different proteoforms represents an interesting alter...

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Bibliographic Details
Published in:Front Neurosci
Main Authors: Bros, Pauline, Vialaret, Jérôme, Barthelemy, Nicolas, Delatour, Vincent, Gabelle, Audrey, Lehmann, Sylvain, Hirtz, Christophe
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2015
Subjects:
Psychiatry
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4555028/
https://ncbi.nlm.nih.gov/pubmed/26388715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2015.00302
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