Interleukin 18 function requires both interleukin 18 receptor and Na-Cl co-transporter

Interleukin-18 (IL18) participates in atherogenesis through several putative mechanisms(1,2). Interruption of IL18 action reduces atherosclerosis in mice(3,4). This study shows that the absence of IL18 receptor (IL18r) does not affect atherosclerosis in apolipoprotein E-deficient (Apoe(−/−)) mice, n...

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Veröffentlicht in:Nat Med
Hauptverfasser: Wang, Jing, Sun, Chongxiu, Gerdes, Norbert, Liu, Conglin, Liao, Mengyang, Liu, Jian, Shi, Michael A., He, Aina, Zhou, Yi, Sukhova, Galina K., Chen, Huimei, Cheng, Xianwu, Kuzuya, Masafumi, Murohara, Toyoaki, Zhang, Jie, Cheng, Xiang, Jiang, Mengmeng, Shull, Gary E., Rogers, Shaunessy, Yang, Chao-Ling, Ke, Qiang, Jelen, Sabina, Bindels, René, Ellison, David H., Jarolim, Petr, Libby, Peter, Shi, Guo-Ping
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4554539/
https://ncbi.nlm.nih.gov/pubmed/26099046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3890
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