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Prolonged Running, not Fluoxetine Treatment, Increases Neurogenesis, but does not Alter Neuropathology, in the 3xTg Mouse Model of Alzheimer’s Disease
Reductions in adult neurogenesis have been documented in the original 3xTg mouse model of Alzheimer’s disease (AD), notably occurring at the same age when spatial memory deficits and amyloid plaque pathology appeared. As this suggested reduced neurogenesis was associated with behavioral deficits, we...
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| Publicado no: | Curr Top Behav Neurosci |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4554490/ https://ncbi.nlm.nih.gov/pubmed/23670818 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/7854_2012_237 |
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