Characterization of the l-alanine exporter AlaE of Escherichia coli and its potential role in protecting cells from a toxic-level accumulation of l-alanine and its derivatives

We previously reported that the alaE gene of Escherichia coli encodes the l-alanine exporter AlaE. The objective of this study was to elucidate the mechanism of the AlaE exporter. The minimum inhibitory concentration of l-alanine and l-alanyl-l-alanine in alaE-deficient l-alanine-nonmetabolizing cel...

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Bibliographic Details
Published in:Microbiologyopen
Main Authors: Kim, Seryoung, Ihara, Kohei, Katsube, Satoshi, Hori, Hatsuhiro, Ando, Tasuke, Isogai, Emiko, Yoneyama, Hiroshi
Format: Artigo
Language:Inglês
Published: John Wiley & Sons, Ltd 2015
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4554458/
https://ncbi.nlm.nih.gov/pubmed/26073055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mbo3.269
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