Photothermal treatment of liver cancer with albumin-conjugated gold nanoparticles initiates Golgi Apparatus–ER dysfunction and caspase-3 apoptotic pathway activation by selective targeting of Gp60 receptor

We present a method of enhanced laser thermal ablation of HepG2 cells based on a simple gold nanoparticle (GNP) carrier system such as serum albumin (Alb), and demonstrate its selective therapeutic efficacy compared with normal hepatocyte cells. HepG2 or hepatocytes were treated with Alb-GNPs at var...

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Bibliografiske detaljer
Udgivet i:Int J Nanomedicine
Main Authors: Mocan, Lucian, Matea, Cristian, Tabaran, Flaviu A, Mosteanu, Ofelia, Pop, Teodora, Mocan, Teodora, Iancu, Cornel
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2015
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4554431/
https://ncbi.nlm.nih.gov/pubmed/26346915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S86495
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