Augmentation of Response to Chemotherapy by microRNA-506 Through Regulation of RAD51 in Serous Ovarian Cancers

BACKGROUND: Chemoresistance is a major challenge in cancer treatment. miR-506 is a potent inhibitor of the epithelial-to-mesenchymal transition (EMT), which is also associated with chemoresistance. We characterized the role of miR-506 in chemotherapy response in high-grade serous ovarian cancers. ME...

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Udgivet i:J Natl Cancer Inst
Main Authors: Liu, Guoyan, Yang, Da, Rupaimoole, Rajesha, Pecot, Chad V., Sun, Yan, Mangala, Lingegowda S., Li, Xia, Ji, Ping, Cogdell, David, Hu, Limei, Wang, Yingmei, Rodriguez-Aguayo, Cristian, Lopez-Berestein, Gabriel, Shmulevich, Ilya, De Cecco, Loris, Chen, Kexin, Mezzanzanica, Delia, Xue, Fengxia, Sood, Anil K., Zhang, Wei
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4554255/
https://ncbi.nlm.nih.gov/pubmed/25995442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djv108
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