Carboxylesterase 2 as a Determinant of Response to Irinotecan and Neoadjuvant FOLFIRINOX Therapy in Pancreatic Ductal Adenocarcinoma

BACKGROUND: Serine hydrolases (SHs) are among the largest classes of enzymes in humans and play crucial role in many pathophysiological processes of cancer. We have undertaken a comprehensive proteomic analysis to assess the differential expression and cellular localization of SHs, which uncovered d...

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Detalhes bibliográficos
Publicado no:J Natl Cancer Inst
Main Authors: Capello, Michela, Lee, Minhee, Wang, Hong, Babel, Ingrid, Katz, Matthew H., Fleming, Jason B., Maitra, Anirban, Wang, Huamin, Tian, Weihua, Taguchi, Ayumu, Hanash, Samir M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4554193/
https://ncbi.nlm.nih.gov/pubmed/26025324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djv132
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