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Mechanical coupling of the multiple structural elements of the large-conductance mechanosensitive channel during expansion

The prokaryotic mechanosensitive channel of large conductance (MscL) is a pressure-relief valve protecting the cell from lysing during acute osmotic downshock. When the membrane is stretched, MscL responds to the increase of membrane tension and opens a nonselective pore to about 30 Å wide, exhibiti...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Li, Jie, Guo, Jianli, Ou, Xiaomin, Zhang, Mingfeng, Li, Yuezhou, Liu, Zhenfeng
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4553819/
https://ncbi.nlm.nih.gov/pubmed/26261325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1503202112
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