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Mechanical coupling of the multiple structural elements of the large-conductance mechanosensitive channel during expansion
The prokaryotic mechanosensitive channel of large conductance (MscL) is a pressure-relief valve protecting the cell from lysing during acute osmotic downshock. When the membrane is stretched, MscL responds to the increase of membrane tension and opens a nonselective pore to about 30 Å wide, exhibiti...
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Publicado no: | Proc Natl Acad Sci U S A |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4553819/ https://ncbi.nlm.nih.gov/pubmed/26261325 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1503202112 |
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