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Structures of two bacterial resistance factors mediating tRNA-dependent aminoacylation of phosphatidylglycerol with lysine or alanine

The cytoplasmic membrane is probably the most important physical barrier between microbes and the surrounding habitat. Aminoacylation of the polar head group of the phospholipid phosphatidylglycerol (PG) catalyzed by Ala-tRNA(Ala)–dependent alanyl-phosphatidylglycerol synthase (A-PGS) or by Lys-tRNA...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Hebecker, Stefanie, Krausze, Joern, Hasenkampf, Tatjana, Schneider, Julia, Groenewold, Maike, Reichelt, Joachim, Jahn, Dieter, Heinz, Dirk W., Moser, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4553816/
https://ncbi.nlm.nih.gov/pubmed/26261323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1511167112
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