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Structures of two bacterial resistance factors mediating tRNA-dependent aminoacylation of phosphatidylglycerol with lysine or alanine

The cytoplasmic membrane is probably the most important physical barrier between microbes and the surrounding habitat. Aminoacylation of the polar head group of the phospholipid phosphatidylglycerol (PG) catalyzed by Ala-tRNA(Ala)–dependent alanyl-phosphatidylglycerol synthase (A-PGS) or by Lys-tRNA...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Hebecker, Stefanie, Krausze, Joern, Hasenkampf, Tatjana, Schneider, Julia, Groenewold, Maike, Reichelt, Joachim, Jahn, Dieter, Heinz, Dirk W., Moser, Jürgen
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4553816/
https://ncbi.nlm.nih.gov/pubmed/26261323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1511167112
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