Structures of two bacterial resistance factors mediating tRNA-dependent aminoacylation of phosphatidylglycerol with lysine or alanine

The cytoplasmic membrane is probably the most important physical barrier between microbes and the surrounding habitat. Aminoacylation of the polar head group of the phospholipid phosphatidylglycerol (PG) catalyzed by Ala-tRNA(Ala)–dependent alanyl-phosphatidylglycerol synthase (A-PGS) or by Lys-tRNA...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Hebecker, Stefanie, Krausze, Joern, Hasenkampf, Tatjana, Schneider, Julia, Groenewold, Maike, Reichelt, Joachim, Jahn, Dieter, Heinz, Dirk W., Moser, Jürgen
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2015
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4553816/
https://ncbi.nlm.nih.gov/pubmed/26261323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1511167112
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