Adiposity as a cause of cardiovascular disease: a Mendelian randomization study

Background: Adiposity, as indicated by body mass index (BMI), has been associated with risk of cardiovascular diseases in epidemiological studies. We aimed to investigate if these associations are causal, using Mendelian randomization (MR) methods. Methods: The associations of BMI with cardiovascula...

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Bibliografiska uppgifter
I publikationen:Int J Epidemiol
Huvudupphovsmän: Hägg, Sara, Fall, Tove, Ploner, Alexander, Mägi, Reedik, Fischer, Krista, Draisma, Harmen HM, Kals, Mart, de Vries, Paul S, Dehghan, Abbas, Willems, Sara M, Sarin, Antti-Pekka, Kristiansson, Kati, Nuotio, Marja-Liisa, Havulinna, Aki S, de Bruijn, Renée FAG, Ikram, M Arfan, Kuningas, Maris, Stricker, Bruno H, Franco, Oscar H, Benyamin, Beben, Gieger, Christian, Hall, Alistair S, Huikari, Ville, Jula, Antti, Järvelin, Marjo-Riitta, Kaakinen, Marika, Kaprio, Jaakko, Kobl, Michael, Mangino, Massimo, Nelson, Christopher P, Palotie, Aarno, Samani, Nilesh J, Spector, Tim D, Strachan, David P, Tobin, Martin D, Whitfield, John B, Uitterlinden, André G, Salomaa, Veikko, Syvänen, Ann-Christine, Kuulasmaa, Kari, Magnusson, Patrik K, Esko, Tõnu, Hofman, Albert, de Geus, Eco JC, Lind, Lars, Giedraitis, Vilmantas, Perola, Markus, Evans, Alun, Ferrières, Jean, Virtamo, Jarmo, Kee, Frank, Tregouet, David-Alexandre, Arveiler, Dominique, Amouyel, Philippe, Gianfagna, Francesco, Brambilla, Paolo, Ripatti, Samuli, van Duijn, Cornelia M, Metspalu, Andres, Prokopenko, Inga, McCarthy, Mark I, Pedersen, Nancy L, Ingelsson, Erik
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2015
Ämnen:
Mendelian Randomization Causal Analysis
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4553708/
https://ncbi.nlm.nih.gov/pubmed/26016847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ije/dyv094
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