Deferoxamine Improves Alveolar and Pulmonary Vascular Development by Upregulating Hypoxia-inducible Factor-1α in a Rat Model of Bronchopulmonary Dysplasia

Fetal lung development normally occurs in a hypoxic environment. Hypoxia-inducible factor (HIF)-1α is robustly induced under hypoxia and transactivates many genes that are essential for fetal development. Most preterm infants are prematurely exposed to hyperoxia, which can halt hypoxia-driven lung m...

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Detalhes bibliográficos
Publicado no:J Korean Med Sci
Main Authors: Choi, Chang Won, Lee, Juyoung, Lee, Hyun Ju, Park, Hyoung-Sook, Chun, Yang-Sook, Kim, Beyong Il
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Academy of Medical Sciences 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4553677/
https://ncbi.nlm.nih.gov/pubmed/26339170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3346/jkms.2015.30.9.1295
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