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Dual Delivery of EPO and BMP2 from a Novel Modular Poly-ɛ-Caprolactone Construct to Increase the Bone Formation in Prefabricated Bone Flaps

Poly-ɛ-caprolactone (PCL) is a biocompatible polymer that has mechanical properties suitable for bone tissue engineering; however, it must be integrated with biologics to stimulate bone formation. Bone morphogenetic protein-2 (BMP2) delivered from PCL produces bone when implanted subcutaneously, and...

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Detalhes bibliográficos
Publicado no:Tissue Eng Part C Methods
Main Authors: Patel, Janki Jayesh, Modes, Jane E., Flanagan, Colleen L., Krebsbach, Paul H., Edwards, Sean P., Hollister, Scott J.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4553374/
https://ncbi.nlm.nih.gov/pubmed/25809081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ten.tec.2014.0643
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