Nuclear heterogeneous nuclear ribonucleoprotein D is associated with poor prognosis and interactome analysis reveals its novel binding partners in oral cancer

BACKGROUND: Post-transcriptional regulation by heterogeneous ribonucleoproteins (hnRNPs) is an important regulatory paradigm in cancer development. Our proteomic analysis revealed hnRNPD overexpression in oral dysplasia as compared with normal mucosa; its role in oral carcinogenesis remains unknown....

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Veröffentlicht in:J Transl Med
Hauptverfasser: Kumar, Manish, Matta, Ajay, Masui, Olena, Srivastava, Gunjan, Kaur, Jatinder, Thakar, Alok, Shukla, Nootan Kumar, RoyChoudhury, Ajoy, Sharma, Meherchand, Walfish, Paul G., Michael Siu, K. W., Chauhan, Shyam Singh, Ralhan, Ranju
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4553214/
https://ncbi.nlm.nih.gov/pubmed/26318153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0637-3
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