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Medication Nonadherence, “Professional Subjects,” and Apparent Placebo Responders: Overlapping Challenges for Medications Development

Nonadherence is a major problem in clinical trials of new medications. To evaluate the extent of nonadherence, this study evaluated pharmacokinetic sampling from 1765 subjects receiving active therapy across eight psychiatric trials conducted between 2001 and 2011. With nonadherence defined as >...

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Detalhes bibliográficos
Publicado no:J Clin Psychopharmacol
Main Authors: McCann, David J., Petry, Nancy M., Bresell, Anders, Isacsson, Eva, Wilson, Ellis, Alexander, Robert C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4553101/
https://ncbi.nlm.nih.gov/pubmed/26244381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JCP.0000000000000372
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