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A Subregion of Reelin Suppresses Lipoprotein-Induced Cholesterol Accumulation in Macrophages

Activation of apolipoprotein E receptor-2 (apoER2) and very low density lipoprotein receptor (VLDLR) inhibits foam cell formation. Reelin is a ligand of these receptors. Here we generated two reelin subregions containing the receptor binding domain with or without its C-terminal region (R5-6C and R5...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Okoro, Emmanuel U., Zhang, Hongfeng, Guo, Zhongmao, Yang, Fang, Smith, Carlie, Yang, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552883/
https://ncbi.nlm.nih.gov/pubmed/26317415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136895
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