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Identifying Driver Genomic Alterations in Cancers by Searching Minimum-Weight, Mutually Exclusive Sets

An important goal of cancer genomic research is to identify the driving pathways underlying disease mechanisms and the heterogeneity of cancers. It is well known that somatic genome alterations (SGAs) affecting the genes that encode the proteins within a common signaling pathway exhibit mutual exclu...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS Comput Biol
Egile Nagusiak: Lu, Songjian, Lu, Kevin N., Cheng, Shi-Yuan, Hu, Bo, Ma, Xiaojun, Nystrom, Nicholas, Lu, Xinghua
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552843/
https://ncbi.nlm.nih.gov/pubmed/26317392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004257
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