Identifying Driver Genomic Alterations in Cancers by Searching Minimum-Weight, Mutually Exclusive Sets

An important goal of cancer genomic research is to identify the driving pathways underlying disease mechanisms and the heterogeneity of cancers. It is well known that somatic genome alterations (SGAs) affecting the genes that encode the proteins within a common signaling pathway exhibit mutual exclu...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS Comput Biol
Prif Awduron: Lu, Songjian, Lu, Kevin N., Cheng, Shi-Yuan, Hu, Bo, Ma, Xiaojun, Nystrom, Nicholas, Lu, Xinghua
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2015
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552843/
https://ncbi.nlm.nih.gov/pubmed/26317392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004257
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