PGC−1α Promoter Methylation in Parkinson’s Disease

The etiopathogenesis of sporadic Parkinson’s disease (PD) remains elusive although mitochondrial dysfunction has long been implicated. Recent evidence revealed reduced expression of peroxisome proliferator-activated receptor gamma coactivator−1 α (PGC−1α) and downstream regulated nuclear encoded res...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Su, Xiaomin, Chu, Yaping, Kordower, Jeffrey H., Li, Bin, Cao, Hong, Huang, Liang, Nishida, Maki, Song, Lei, Wang, Difei, Federoff, Howard J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552803/
https://ncbi.nlm.nih.gov/pubmed/26317511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134087
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