Usefulness of Time-Point Serum Cortisol and ACTH Measurements for the Adjustment of Glucocorticoid Replacement in Adrenal Insufficiency

BACKGROUND: Adjustment of daily hydrocortisone dose on clinical criteria lacks sensitivity for fine tuning. Long term hydrocortisone (HC) over-replacement may lead to increased morbidity and mortality in patients with adrenal insufficiency (AI). Biochemical criteria may help detecting over- or under...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Rousseau, Elise, Joubert, Michael, Trzepla, Géraldine, Parienti, Jean Jacques, Freret, Thomas, Vanthygem, Marie Christine, Desailloud, Rachel, Lefebvre, Hervé, Coquerel, Antoine, Reznik, Yves
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552782/
https://ncbi.nlm.nih.gov/pubmed/26317782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135975
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