A Biochemical Approach to Understand the Pathogenesis of Advanced Pulmonary Arterial Hypertension: Metabolomic Profiles of Arginine, Sphingosine-1-Phosphate, and Heme of Human Lung

Pulmonary arterial hypertension (PAH) is a vascular disease characterized by persistent precapillary pulmonary hypertension (PH), leading to progressive right heart failure and premature death. The pathological mechanisms underlying this condition remain elusive. Analysis of global metabolomics from...

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Udgivet i:PLoS One
Main Authors: Zhao, Yidan D., Chu, Lei, Lin, Kathleen, Granton, Elise, Yin, Li, Peng, Jenny, Hsin, Michael, Wu, Licun, Yu, Amy, Waddell, Thomas, Keshavjee, Shaf, Granton, John, de Perrot, Marc
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552732/
https://ncbi.nlm.nih.gov/pubmed/26317340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134958
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