CD8(+) T Cell Response to Gammaherpesvirus Infection Mediates Inflammation and Fibrosis in Interferon Gamma Receptor-Deficient Mice

Idiopathic pulmonary fibrosis (IPF), one of the most severe interstitial lung diseases, is a progressive fibrotic disorder of unknown etiology. However, there is growing appreciation for the role of viral infection in disease induction and/or progression. A small animal model of multi-organ fibrosis...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: O’Flaherty, Brigid M., Matar, Caline G., Wakeman, Brian S., Garcia, AnaPatricia, Wilke, Carol A., Courtney, Cynthia L., Moore, Bethany B., Speck, Samuel H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552722/
https://ncbi.nlm.nih.gov/pubmed/26317335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135719
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