Genomic landscape of cutaneous T cell lymphoma

Cutaneous T cell lymphoma (CTCL) is a non-Hodgkin lymphoma of skin-homing T lymphocytes. We performed exome and whole genome DNA sequence and RNA sequencing on purified CTCL and matched normal cells. The results implicate mutations in 17 genes in CTCL pathogenesis, including genes involved in T cell...

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Bibliografiska uppgifter
I publikationen:Nat Genet
Huvudupphovsmän: Choi, Jaehyuk, Goh, Gerald, Walradt, Trent, Hong, Bok S., Bunick, Christopher G., Chen, Kan, Bjornson, Robert D., Maman, Yaakov, Wang, Tiffany, Tordoff, Jesse, Carlson, Kacie, Overton, John D., Liu, Kristina J., Lewis, Julia M., Devine, Lesley, Barbarotta, Lisa, Foss, Francine M., Subtil, Antonio, Vonderheid, Eric C., Edelson, Richard L., Schatz, David G., Boggon, Titus J., Girardi, Michael, Lifton, Richard P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552614/
https://ncbi.nlm.nih.gov/pubmed/26192916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3356
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