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Genomic landscape of cutaneous T cell lymphoma

Cutaneous T cell lymphoma (CTCL) is a non-Hodgkin lymphoma of skin-homing T lymphocytes. We performed exome and whole genome DNA sequence and RNA sequencing on purified CTCL and matched normal cells. The results implicate mutations in 17 genes in CTCL pathogenesis, including genes involved in T cell...

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Détails bibliographiques
Publié dans:Nat Genet
Auteurs principaux: Choi, Jaehyuk, Goh, Gerald, Walradt, Trent, Hong, Bok S., Bunick, Christopher G., Chen, Kan, Bjornson, Robert D., Maman, Yaakov, Wang, Tiffany, Tordoff, Jesse, Carlson, Kacie, Overton, John D., Liu, Kristina J., Lewis, Julia M., Devine, Lesley, Barbarotta, Lisa, Foss, Francine M., Subtil, Antonio, Vonderheid, Eric C., Edelson, Richard L., Schatz, David G., Boggon, Titus J., Girardi, Michael, Lifton, Richard P.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552614/
https://ncbi.nlm.nih.gov/pubmed/26192916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3356
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