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Genomic landscape of cutaneous T cell lymphoma

Cutaneous T cell lymphoma (CTCL) is a non-Hodgkin lymphoma of skin-homing T lymphocytes. We performed exome and whole genome DNA sequence and RNA sequencing on purified CTCL and matched normal cells. The results implicate mutations in 17 genes in CTCL pathogenesis, including genes involved in T cell...

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Detalhes bibliográficos
Publicado no:Nat Genet
Main Authors: Choi, Jaehyuk, Goh, Gerald, Walradt, Trent, Hong, Bok S., Bunick, Christopher G., Chen, Kan, Bjornson, Robert D., Maman, Yaakov, Wang, Tiffany, Tordoff, Jesse, Carlson, Kacie, Overton, John D., Liu, Kristina J., Lewis, Julia M., Devine, Lesley, Barbarotta, Lisa, Foss, Francine M., Subtil, Antonio, Vonderheid, Eric C., Edelson, Richard L., Schatz, David G., Boggon, Titus J., Girardi, Michael, Lifton, Richard P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552614/
https://ncbi.nlm.nih.gov/pubmed/26192916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3356
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