Local microRNA modulation using a novel anti-miR-21-eluting stent effectively prevents experimental in-stent restenosis

OBJECTIVE: Despite advances in stent technology for vascular interventions, in-stent restenosis (ISR) due to myointimal hyperplasia (MH) remains a major complication. APPROACH AND RESULTS: We investigated the regulatory role of microRNAs in MH/ISR, utilizing a humanized animal model in which balloon...

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Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Wang, Dong, Deuse, Tobias, Stubbendorff, Mandy, Chernogubova, Ekaterina, Erben, Reinhold G., Eken, Suzanne M., Jin, Hong, Li, Yuhuang, Busch, Albert, Heeger, Christian H., Behnisch, Boris, Reichenspurner, Hermann, Robbins, Robert C., Spin, Joshua M., Tsao, Philip S., Schrepfer, Sonja, Maegdefessel, Lars
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552606/
https://ncbi.nlm.nih.gov/pubmed/26183619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.115.305597
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