Low miR-143/miR-145 Cluster Levels Induce Activin A Overexpression in Oral Squamous Cell Carcinomas, Which Contributes to Poor Prognosis

Deregulated expression of activin A is reported in several tumors, but its biological functions in oral squamous cell carcinoma (OSCC) are unknown. Here, we investigate whether activin A can play a causal role in OSCCs. Activin A expression was assessed by qPCR and immunohistochemistry in OSCC tissu...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Bufalino, Andreia, Cervigne, Nilva K., de Oliveira, Carine Ervolino, Fonseca, Felipe Paiva, Rodrigues, Priscila Campioni, Macedo, Carolina Carneiro Soares, Sobral, Lays Martin, Miguel, Marcia Costa, Lopes, Marcio Ajudarte, Leme, Adriana Franco Paes, Lambert, Daniel W., Salo, Tuula A., Kowalski, Luiz Paulo, Graner, Edgard, Coletta, Ricardo D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552554/
https://ncbi.nlm.nih.gov/pubmed/26317418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136599
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