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Leukotriene D(4)-induced Caco-2 cell proliferation is mediated by prostaglandin E(2) synthesis
Leukotriene D(4) (LTD(4)) is a pro-inflammatory mediator formed from arachidonic acid through the action of 5-lipoxygenase (5-LOX). Its biological effects are mediated by at least two G-coupled plasmatic cysteinyl LT receptors (CysLT(1-2)R). It has been reported an upregulation of the 5-LOX pathway...
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| Publicado no: | Physiol Rep |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley & Sons, Ltd
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4552517/ https://ncbi.nlm.nih.gov/pubmed/26216432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12417 |
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