C5a alters blood–brain barrier integrity in a human in vitro model of systemic lupus erythematosus

The blood–brain barrier (BBB) plays a crucial role in brain homeostasis, thereby maintaining the brain environment precise for optimal neuronal function. Its dysfunction is an intriguing complication of systemic lupus erythematosus (SLE). SLE is a systemic autoimmune disorder where neurological comp...

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Detalhes bibliográficos
Publicado no:Immunology
Main Authors: Mahajan, Supriya D, Parikh, Neil U, Woodruff, Trent M, Jarvis, James N, Lopez, Molly, Hennon, Teresa, Cunningham, Patrick, Quigg, Richard J, Schwartz, Stanley A, Alexander, Jessy J
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552508/
https://ncbi.nlm.nih.gov/pubmed/26059553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12489
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