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Systemic EP4 Inhibition Increases Adhesion Formation in a Murine Model of Flexor Tendon Repair

Flexor tendon injuries are a common clinical problem, and repairs are frequently complicated by post-operative adhesions forming between the tendon and surrounding soft tissue. Prostaglandin E2 and the EP4 receptor have been implicated in this process following tendon injury; thus, we hypothesized t...

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Bibliographic Details
Published in:PLoS One
Main Authors: Geary, Michael B., Orner, Caitlin A., Bawany, Fatima, Awad, Hani A., Hammert, Warren C., O’Keefe, Regis J., Loiselle, Alayna E.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552471/
https://ncbi.nlm.nih.gov/pubmed/26312751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136351
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