Unraveling Comparative Anti-Amyloidogenic Behavior of Pyrazinamide and D-Cycloserine: A Mechanistic Biophysical Insight

Amyloid fibril formation by proteins leads to variety of degenerative disorders called amyloidosis. While these disorders are topic of extensive research, effective treatments are still unavailable. Thus in present study, two anti-tuberculosis drugs, i.e., pyrazinamide (PYZ) and D-cycloserine (DCS),...

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Bibliographic Details
Published in:PLoS One
Main Authors: Chaturvedi, Sumit Kumar, Zaidi, Nida, Alam, Parvez, Khan, Javed Masood, Qadeer, Atiyatul, Siddique, Ibrar Ahmad, Asmat, Shamoon, Zaidi, Yusra, Khan, Rizwan Hasan
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552381/
https://ncbi.nlm.nih.gov/pubmed/26312749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136528
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