Unraveling Comparative Anti-Amyloidogenic Behavior of Pyrazinamide and D-Cycloserine: A Mechanistic Biophysical Insight

Amyloid fibril formation by proteins leads to variety of degenerative disorders called amyloidosis. While these disorders are topic of extensive research, effective treatments are still unavailable. Thus in present study, two anti-tuberculosis drugs, i.e., pyrazinamide (PYZ) and D-cycloserine (DCS),...

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Publicat a:PLoS One
Autors principals: Chaturvedi, Sumit Kumar, Zaidi, Nida, Alam, Parvez, Khan, Javed Masood, Qadeer, Atiyatul, Siddique, Ibrar Ahmad, Asmat, Shamoon, Zaidi, Yusra, Khan, Rizwan Hasan
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552381/
https://ncbi.nlm.nih.gov/pubmed/26312749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136528
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