Two separable functions of Ctp1 in the early steps of meiotic DNA double-strand break repair

Meiotic programmed DNA double-strand break (DSB) repair is essential for crossing-over and viable gamete formation and requires removal of Spo11-oligonucleotide complexes from 5′ ends (clipping) and their resection to generate invasive 3′-end single-stranded DNA (resection). Ctp1 (Com1, Sae2, CtIP h...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Ma, Lijuan, Milman, Neta, Nambiar, Mridula, Smith, Gerald R.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2015
Subjects:
Genome Integrity, Repair and Replication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4551917/
https://ncbi.nlm.nih.gov/pubmed/26130711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv644
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