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Differential regulation of octamer-containing cellular genes by the herpes simplex virus virion protein Vmw65 is mediated by sequence differences in the octamer element.

The gene encoding the U3 SnRNA is transcriptionally induced early in infection with herpes simplex virus (HSV). This effect is due to the action of the HSV virion protein Vmw65 and is dependent upon the octamer motif in the U3 promoter. In contrast the U1 SnRNA gene which also contains an octamer is...

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Bibliographic Details
Main Authors: Kemp, L M, Latchman, D S
Format: Artigo
Language:Inglês
Published: 1988
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC455137/
https://ncbi.nlm.nih.gov/pubmed/2854059
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