Direct combinatorial interaction between a herpes simplex virus regulatory protein and a cellular octamer-binding factor mediates specific induction of virus immediate-early gene expression.

We provide evidence for a novel mechanism of transcriptional regulation in which the immediate-early (IE) transactivating protein of herpes simplex virus, Vmw65, is assembled into a specific DNA-binding complex together with a cellular octamer-binding factor (TRF). The assembly of Vmw65/TRF complex...

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Detalhes bibliográficos
Publicado no:EMBO J
Principais autores: O'Hare, P, Goding, C R, Haigh, A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1988
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC455136/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2854058/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1988.tb03320.x
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