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Deferoxamine, Cerebrovascular Hemodynamics and Vascular Aging: Potential Role for HIF-1 Regulated Pathways

BACKGROUND AND PURPOSE: Iron chelation therapy is emerging as a novel neuroprotective strategy. The mechanisms of neuroprotection are diverse and include both neuronal and vascular pathways. We sought to examine the effect of iron chelation on cerebrovascular function in healthy aging and to explore...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Stroke
Hauptverfasser: Sorond, Farzaneh A., Tan, Can Ozan, LaRose, Sarah, Monk, Andrew D., Fichorova, Raina, Ryan, Stanthia, Lipsitz, Lewis A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4551113/
https://ncbi.nlm.nih.gov/pubmed/26304864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.115.009906
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