Identification of agents effective against multiple toxins and viruses by host-oriented cell targeting

A longstanding and still-increasing threat to the effective treatment of infectious diseases is resistance to antimicrobial countermeasures. Potentially, the targeting of host proteins and pathways essential for the detrimental effects of pathogens offers an approach that may discover broad-spectrum...

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Vydáno v:Sci Rep
Hlavní autoři: Zilbermintz, Leeor, Leonardi, William, Jeong, Sun-Young, Sjodt, Megan, McComb, Ryan, Ho, Chi-Lee C., Retterer, Cary, Gharaibeh, Dima, Zamani, Rouzbeh, Soloveva, Veronica, Bavari, Sina, Levitin, Anastasia, West, Joel, Bradley, Kenneth A., Clubb, Robert T., Cohen, Stanley N., Gupta, Vivek, Martchenko, Mikhail
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4550849/
https://ncbi.nlm.nih.gov/pubmed/26310922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13476
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