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The RNA-binding protein Sam68 regulates expression and transcription function of the androgen receptor splice variant AR-V7

Castration-resistant (CR) prostate cancer (PCa) partly arises due to persistence of androgen receptor (AR) transcriptional activity in the absence of cognate ligand. An emerging mechanism underlying the CRPCa phenotype and predicting response to therapy is the expression of the constitutively-active...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Stockley, Jacqueline, Markert, Elke, Zhou, Yan, Robson, Craig N., Elliott, David J., Lindberg, Johan, Leung, Hing Y., Rajan, Prabhakar
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4550848/
https://ncbi.nlm.nih.gov/pubmed/26310125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13426
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