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Early adversity disrupts the adult use of aversive prediction errors to reduce fear in uncertainty

Early life adversity increases anxiety in adult rodents and primates, and increases the risk for developing post-traumatic disorder (PTSD) in humans. We hypothesized that early adversity impairs the use of learning signals -negative, aversive prediction errors–to reduce fear in uncertainty. To test...

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Detalhes bibliográficos
Publicado no:Front Behav Neurosci
Main Authors: Wright, Kristina M., DiLeo, Alyssa, McDannald, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4550796/
https://ncbi.nlm.nih.gov/pubmed/26379520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnbeh.2015.00227
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