Disseminated Medulloblastoma in a Child with Germline BRCA2 6174delT Mutation and without Fanconi Anemia

Medulloblastoma, the most common malignant brain tumor in children, occurs with increased frequency in individuals with Fanconi anemia who have biallelic germline mutations in BRCA2. We describe an 8-year-old child who had disseminated anaplastic medulloblastoma and a deleterious heterozygous BRCA2...

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Vydáno v:Front Oncol
Hlavní autoři: Xu, Jingying, Margol, Ashley Sloane, Shukla, Anju, Ren, Xiuhai, Finlay, Jonathan L., Krieger, Mark D., Gilles, Floyd H., Couch, Fergus J., Aziz, Meraj, Fung, Eric T., Asgharzadeh, Shahab, Barrett, Michael T., Erdreich-Epstein, Anat
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2015
Témata:
Oncology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4550790/
https://ncbi.nlm.nih.gov/pubmed/26380221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2015.00191
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