Staphylococcus aureus Biofilms Induce Macrophage Dysfunction Through Leukocidin AB and Alpha-Toxin

The macrophage response to planktonic Staphylococcus aureus involves the induction of proinflammatory microbicidal activity. However, S. aureus biofilms can interfere with these responses in part by polarizing macrophages toward an anti-inflammatory profibrotic phenotype. Here we demonstrate that co...

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Publicado en:mBio
Main Authors: Scherr, Tyler D., Hanke, Mark L., Huang, Ouwen, James, David B. A., Horswill, Alexander R., Bayles, Kenneth W., Fey, Paul D., Torres, Victor J., Kielian, Tammy
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Microbiology 2015
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4550693/
https://ncbi.nlm.nih.gov/pubmed/26307164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01021-15
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